Protein synthesis in the rumen: Ruminal urease inhibition by acetohydroxamic acid
Adepoju, A.; Portela, F.; Brent, B.E.
When urea is fed to ruminants, it is immediately converted
to ammonia by an enzyme, urease. The ammonia usually
becomes available faster than rumen bacteria can convert it
to protein. Studies were reported last year (Bulletin 518)
on attempts to slow down, or inhibit urease with acetohydroxamic
acid.
This year effects of acetohydroxamic acid on rumen
ammonia, and volatile fatty acid levels in both sheep and
cattle have been studied. In both, rumen ammonia was depressed
for about 4 hours after feeding, and rumen fluid
urea levels were increased, showing that urease was inhibited.
Ammonia data for the steers showed no cumulative
effect from prolonged use of acetohydroxamic acid, and no
residual effect when it was withdrawn from the ration.
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